In the bone marrow, immature RBC's mitochondria surround the nucleus and get laden with excess iron deposits, which produces ringed sideroblasts on histology, hence the name of the disease.

在骨髓中，幼红细胞的线粒体围绕着细胞核，并且充盈着大量的铁沉积物，在组织学上形成环状的铁粒幼红细胞，铁粒幼细胞性贫血也因此得名。

These sideroblasts of ineffective erythropoiesis, which means they don't develop normally to become a mature RBC, and end up dying in the bone marrow, with a few escaping into the peripheral blood.

这些红细胞生成无效的铁粒幼红细胞，也就是说它们不能正常发育为成熟的红细胞，大多会最终在骨髓中死亡，少量逸出到外周血中。