These are diseases like sickle cell anemia or beta thalassemia.

比如镰状细胞性贫血或β地中海贫血。

Taita-Taveta has an alarming rate of sickle cell disease.

Taita-Taveta已对该疾病的出现亮起警示灯。

We are solving sickle cell in a holistic way.

我们正在以整体的方式治疗镰刀细胞疾病。

Now imagine that his future wife is a carrier of the sickle cell gene.

现在想象一下，他未来的妻子是镰状细胞基因的携带者。

But there is a good chance she will pass on the sickle cell gene.

但是她很有可能会遗传镰状细胞基因。

So it starts where the places that have the worst effects of sickle cell are.

所以计划首先从那些镰状细胞病影响最严重的地区开始。

Take sickle cell anemia: The gene behind this condition also protects against malaria.

导致这种疾病的基因也能预防疟疾。

Access to care for sickle cell is very far away, and the government has very little resources.

但是想要接受镰刀细胞疾病的医学治疗实际上有些天方夜谭，政府几乎没有资源进行救助。

Sickle cell disease is caused by defective hemoglobin, which is the oxygen-carrying protein in red blood cells.

镰状细胞病是由有缺陷的血红蛋白引起，后者是红细胞中的携氧蛋白。

To treat sickle cell disease, researchers used CRISPR to make the body produce the fetal form of hemoglobin.

为了治疗镰状细胞病，研究人员使用 CRISPR 使身体产生胎儿形式的血红蛋白。

Life in Nigeria had already shown him that sickle cell disease was fated by birth, not by upbringing.

尼日利亚的生活已经告诉他，镰状细胞病是先天的，而不是后天发生。

It found that some of the 27 had possible genes for genetic conditions like sickle cell anemia and G6PD deficiency.

研究发现，这27个人中的一些人可能存在镰状细胞性贫血和G6PD缺乏症等遗传病的基因。

Given all these symptoms, it's important to diagnose sickle cell as early as possible.

鉴于以上症状，尽早诊断镰贫十分重要。

And with the technology and cost involved in this trial, it's unlikely to help sickle cell patients in poor countries.

考虑到这项试验涉及的技术和成本，对于贫穷国家的镰状细胞病患者可能帮助不大。

" the United States … has really taken bold leadership in bringing sickle cell disease to the forefront, " said Admiral Giroir.

" 美国真正勇敢地带头把镰状细胞病放在最优先处置的地位。" 吉罗伊尔上将表示。

Fortunately, as this “adaptation” thrives, our treatment for sickle cell continues to improve.

幸运的是，随着这种“适应” 的蓬勃发展，我们对镰状细胞的治疗也在不断改进。

Later, they get stuck in other bones, causing sickle cell pain crises or avascular necrosis of the bone.

随后，它们嵌顿在其它骨骼，造成镰状细胞疼痛危象或骨骼无血管坏死。

He was inspired by his time as a junior doctor when sickle cell treatment was basic.

当镰状细胞治疗是基本治疗时，他作为一名初级医生的时间受到了启发。

It’s one of the Millennium Development Goals and gives sickle cell newborns a better chance of survival.

这是千年发展目标之一， 为镰状细胞新生儿提供了更好的生存机会。

Millions suffer from sickle cell anemia because they have a single A to T point mutations in both copies of their hemoglobin gene.

数百万人患有镰状细胞性贫血，因为他们的血红蛋白基因的两个拷贝都有一个A点到T点的突变。