Oh, man. Must've had a few screws loose. And the bookshelf too.

噢，天哪。一定是有几个螺丝松了。还有书架也松了。

He knew, no doubt, that there was some screw loose, but he was not in our secrets.

当然，他可能看得出来这里面有些蹊跷，可是我们的秘密他是不知道的。

Oh, dear, sweet, sober Caroline Abbott has a screw loose!

哦，亲爱的，可爱的，清醒的 Caroline Abbott 有一个螺丝松了！

That ball of fluff got a screw loose.

这绒毛球疯了。

They always had a good time, and the bad boys had the broken legs; but in his case there was a screw loose somewhere, and it all happened just the other way.

他们总是玩得很开心， 坏男孩的腿断了；但是在他的情况下， 某个地方的螺丝松了， 一切都以相反的方式发生了。