Unfortunately, though, over time as the oligodendrocytes die off the remyelination stops and the damage becomes irreversible with the loss of axons.

病情长期下去因为少突胶质细胞的死亡，髓鞘将停止再生，并且随着神经元轴索的减少，这些损伤不可逆。

For example, during a bout a person may lose some vision, but then it may be followed by improvement if there's remyelination.

例如，在一次发作期间，患者可能视力下降，但是如果伴随髓鞘再生，病情会有改善。

Early on in multiple sclerosis, the oligodendrocytes will heal and extend out new myelin to cover the neurons, which is a process called remyelination.

多发性硬化早期，少突胶质细胞可以自我修复，形成新髓鞘包裹住神经元，叫作髓鞘再生。

Unfortunately, though, more often than not, the remyelination process is not complete so there is often some residual disability that remains, and that means that with each attach, more and more of the central nervous system gets irreversibly damaged.

不幸的是，髓鞘再生往往是不完全的，所以常常遗留功能障碍，这意味着每次攻击下，越来越多的中枢神经系统区域最终将形成不可逆损伤。