Mrs. Sykes is indicating peripheral neuropathy.

赛克斯夫人表示患有周围神经病变。

In the peripheral nervous system, they can cause peripheral neuropathy and paresthesia which is numbness and prickling sensations, particularly in the legs and feet.

在外周神经系统，它可以导致外周神经病变与感觉异常，比如麻木、刺痛的感觉，特别是在腿和脚部。