In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

转移性黑素瘤患者可发生全身性皮肤黑变（皮肤播散性黑变），通常存在黑尿。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

当其他的鉴别风险因子算术的控制后，转移瘤切除术对有肺转移性黑色素瘤患者仍有显著的生存优势。