Many at-risk HIV negative people across the world do not have access to PrEP or ARVs, and those who are HIV positive may experience challenges to taking ARVs.

世界各地许多处于危险中的艾滋病毒阴性者无法获得暴露前预防或抗逆转录病毒药物，而艾滋病毒感染者也面临服用药物的挑战。