The correct answer is A, to have a low opinion of someone.

正确答案是A，轻视某人。

But look, Chandler... ...right now no one has a lower opinion of you than I do.

听我说，钱德… 现在没有人比我更看不起你。

Americans have a low opinion of comic writers?

大部分美国人瞧不起漫画作家吗？

To look down on someone is to have a low opinion of them or to think that you're better than them in some way.

瞧不起某人的意思是看不上某个人，或者是觉得你在某个方面比他们好。

You likely feel more confident in some circumstances than others, and people tend to be especially sensitive to rejection in situations where they have a low opinion of themselves.

在某种场合下，你可能会比别人更有自信，在对自己缺乏自信的情况下，人们会对遭到拒绝尤为敏感。

So does it mean to have a low opinion of someone, to watch someone from a higher position like maybe up on a balcony or to avoid eye contact because you don't want to look at someone?

那么，它的意思是对某个人不屑一顾，在比较高的位置看某个人（例如在阳台上），还是因为不想看某人而避免目光接触呢？