This is heard loudest in the aortic valve and pulmonary valve area.

这个声音可以在主动脉瓣和肺动脉瓣听诊区被清晰地听到。

The aortic valve can sometimes get inflamed and damaged, leading to aortic regurgitation.

有时主动脉瓣也会被炎症侵及并被破坏，导致主动脉瓣关闭不全。

Recent studies show that most aortic valve surgeries are done by a catheter than more dangerous open-heart surgery.

最近有多项研究表明，大多数主动脉瓣手术是通过导管完成的，而非危险性更高的开胸手术。

And to do that, the aortic valve, on the left side, and the pulmonic valve, on the right side, quietly open up.

为泵出血液，左边的主动脉瓣以及右边的肺动脉瓣安静地打开。

I think I know a thing or two about aortic valve replacements.

我想我对主动脉瓣置换术略知一二。

Aortic valve stenosis, when the aortic valve does not open properly and blood is forced through a narrow opening.

主动脉瓣狭窄，当主动脉瓣不恰当打开时，血液勉强通过狭窄的开口。

An example of diastolic murmurs is aortic valve regurgitation.

舒张期杂音的一个例子是主动脉瓣反流。

The aorta dilates over time, which is a risk for aortic valve insufficiency, where blood leaks back into the left ventricle during diastole.

主动脉逐渐扩张，这是主动脉瓣关闭不全的危险因素之一；这种情况下，舒张期时血将反流至左心室。

He lifted massively heavyweights, and it turned his aortic valve, the one that looks like a Mercedes sign, into a bicuspid double triangular flap.

他能举起巨大的重物，使用类固醇把他的主动脉瓣，那个看起来像梅赛德斯标志的瓣膜，变成了只有一个二尖瓣膜，两个三尖瓣膜。

So during inspiration, the closing of the pulmonary valve is heard slightly later than the aortic valve, and that's called the physiologic splitting of the S2.

所以在吸气时，肺动脉的关闭声，略晚于主动脉的关闭声，这被称作S2的生理性分裂。

Finally, blood in the left ventricle gets pumped out through the aortic valve, which normally has three cusps out to the aorta, the largest artery in the body.

最后，左心室的血液通过主动脉瓣（通常有三个尖瓣）进入身体最大的动脉：主动脉。

This is when the aortic valve does not closse properly, resulting in blood flowing back to the left ventricle during diastole- the filling phase.

这是当主动脉瓣关闭不全时，血液在舒张期——充盈时相反流至左心室产生的。

Right after the S1 sound, the aortic and pulmonic valve open up allowing blood to get pushed out to the body and this period of time is called systole.

在S1之后，主动脉瓣和肺动脉瓣打开，分别使得血液流入身体各组织以及肺部，这段时期叫做心脏收缩期。

Coarctation of the aorta and a bicuspid aortic valve can cause lower extremity cyanosis, meaning a bluish or purplish discoloration of the lower limbs, and can result in congestive heart failure.

主动脉缩窄和二叶式主动脉瓣畸形会导致下肢紫绀，意味着下肢呈青紫色，并可导致充血性心力衰竭。

The second heart sound " dub" , or S2, originates from the closing of the aortic and pulmonary valves, right after the ventricles have ejected the blood.

第二心音“dub”， 即S2，是心室射血之后由于主动脉瓣和肺动脉瓣关闭产生的。

There are also plenty of other unidentified genes on the X chromosome, so individuals with Turner syndrome are predisposed to cardiovascular defects like preductal coarctation of the aorta and bicuspid aortic valve.

X染色体上还有很多其它未被识别的基因，所以特纳综合征患者容易出现心血管缺陷疾病，如导管前型主动脉缩窄、二叶式主动脉瓣畸形。

If you place a stethoscope between the second and third rib, known as the right second intercostal space, just next to the upper border of the sternum, you'll hear the aortic valve closing.

如果你将听诊器置于第二肋及第三肋之间，被称为右第二肋间隙；紧靠胸骨上缘，你将听到主动脉瓣关闭的声音。

Concentric hypertrophy leading to diastolic failure can also be caused by aortic stenosis, which is a narrowing of the aortic valve opening, as well by hypertrophic cardiomyopathy, an abnormal ventricular wall thickening often from a genetic cause.

导致舒张性心衰的向心性肥大，也可能由主动脉瓣狭窄（即主动脉瓣开口变窄）造成，也可能由肥厚型心肌病（一种遗传性异常心室壁增厚）引起。

The second heart sound, " dub" , is called S2, and the noise comes from the aortic and pulmonic valves snapping shut to prevent blood from flowing backwards after it leaves the ventricles, effectively ending systole.

第二心音“dub”，它被称为S2，声音来自主动脉瓣和肺动脉瓣关闭，以防止血液在离开心室后反流，有效地结束心脏收缩。