Recycling of that heme group yields unconjugated bilirubin, which at high concentration can cause scleral icterus, jaundice, and bilirubin gall stones.

亚铁血红素的循环利用会产生非结合胆红素，其浓度过高会导致巩膜黄染、黄疸与胆红素胆结石。