Ghon complexes are usually subpleural and occurred in the lower lobes of the lungs.

肺部原发病灶经常发生于胸膜后，位于肺叶的下叶。

This area is known as a Ghon focus.

这个区域又称之为冈式病灶。

And together this caseating tissue and associated lymph node make up the characteristic Ghon complex.

这些酪化的组织和相关的淋巴结组成典型的肺部原发病灶。

This calcified Ghon complex is called a Ranke complex.

这种钙化的原发病灶也被称为原发综合征。

TB also gets the nearby hilar lymph nodes, either carried over by immune cells through the lymph or by direct extension of the Ghon focus infection and causes caseation there as well.

TB也会进入到临近的肺门淋巴结，它不是被免疫细胞带到淋巴结内，就是直接扩散到冈式病灶里面，在其中产生酪化作用。

If and when a person's immune system becomes compromised like with AIDS or with aging, the Ghon focus can become reactivated and the infection can spread to either one or both upper lobes of the lungs.

当一个人的机体免疫力受损时，例如罹患AIDS或年纪变大，冈式病灶会重新活跃并且感染会扩散到一或多个上肺叶。