Other choices include prokinetic medications, which increase the tone of the lower esophageal sphincter, and the GABA agonist baclofen, which inhibits transient LES relaxations, especially after meals.

其他选择包括促胃肠动力药，这会增加食管下括约肌的张力，以及GABA激动剂巴氯芬，它能抑制一过性LES松弛，尤其是在饭后。