The genetic mutations found most often in serous carcinoma involve the TP53 gene, another tumor suppressor, and aneuploidy, or an abnormal number of chromosomes after cell division.

浆液性癌最常见的基因突变包括TP53基因，也是一个抑癌基因，以及非整倍体，即细胞分裂后染色体数目异常。