Xanthone was efficiently synthesized from o-chlorobenzoic acid first by etherization and then by Friedel-Crafts reaction in the presence of aluminium trichloride.

以邻氯苯甲酸为原料,先进行醚化,再在三氯化铝的作用下进行傅-克反应,可简洁、高效的合成呫吨酮。