Three strategies (additive, chiral auxiliary or chiral reagent) were developed to improve the diastereoselectivity or enantioselectivity of the ylide cyclopropanation reactions.

通过添加剂、手性辅基、手性试剂等3种策略,分别控制反应的非对映选择性和对映选择性。

The enantioselectivity of N-dodecanoyl-L-proline-3,5-dimethyl-anilide is also good, but the basic line fluctuates strongly due to containing benzene ring in its molecular structure.

虽然用N-十二酰基-L-脯氨酸-3,5-二甲基苯胺作添加剂，手性选择性也较好，但由于含有苯环，紫外吸收增强，基线波动严重。