Once bound by IgE the mast cells are " primed" , meaning if pollen enters the body again in the future, those mast cells degranulate and release their histamine into the local tissue.

肥大细胞与IgE型抗体结合后进入致敏状态，当花粉再次侵入机体时，肥大细胞将脱颗粒并将组胺释放到周围组织。